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Medications

Tiopronin delayed-release tablets

What is this medicine?

TIOPRONIN (tye oh PROE nin) binds with cystine in the body. It is used to prevent kidney stones in patients with cystinuria.

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take it with or without food. If it upsets your stomach, take it with food. Do not cut, crush, or chew this medicine. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • dark urine

  • fever

  • joint pain

  • mouth sores

  • redness, blistering, peeling or loosening of the skin, including inside the mouth

  • signs and symptoms of low red blood cells or anemia such as unusually weak or tired; feeling faint or lightheaded; falls; breathing problems

  • swelling of the ankles, feet, hands

  • swollen or painful glands

  • trouble passing urine or change in the amount of urine

  • unusual bruising or bleeding

Side effects that usually do not require medical attention (Report these to your doctor or health care professional if they continue or are bothersome.):

  • changes in taste

  • diarrhea

  • nausea, vomiting

  • tiredness

  • upset stomach

  • wrinkling or thinning of the skin

What may interact with this medicine?

  • alcohol

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep this medicine in the original container. Throw away any unused medicine after the expiration date.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • kidney disease

  • an unusual or allergic reaction to tiopronin, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Visit your healthcare professional for regular checks on your progress. Tell your healthcare professional if your symptoms do not start to get better or if they get worse. You may need blood work and urine tests done while you are taking this medicine.

You may need to be on a special diet while you are taking this medicine. Talk to your doctor about the foods that you eat and the vitamins that you take. Also, ask your doctor how much fluid you need to drink. Drink the recommended amount of fluid each day to stay hydrated and to help prevent kidney stones.

Do not breast-feed an infant while taking this medicine.


NOTE:This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Copyright© 2019 Elsevier